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Humoral immune response to heat shock protein 60 of Aggregatibacter actinomycetemcomitans and cross-reactivity with malondialdehyde acetaldehyde-modified LDL
Atherosclerosis is a chronic inflammatory disease and major cause of mortality worldwide. One of the crucial steps for atherosclerotic plaque development is oxidation of low-density lipoprotein (LDL). Through the oxidation, highly immunogenic epitopes are created and the immune system is activated....
Autores principales: | Kyrklund, Mikael, Bildo, Mika, Akhi, Ramin, Nissinen, Antti E., Pussinen, Pirkko, Hörkkö, Sohvi, Wang, Chunguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094845/ https://www.ncbi.nlm.nih.gov/pubmed/32210456 http://dx.doi.org/10.1371/journal.pone.0230682 |
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