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Viral infections in interferon-γ receptor deficiency()()

Interferon-γ receptor deficiency is a recently described immunodeficiency that is associated with onset of severe mycobacterial infections in childhood. We describe the occurrence of symptomatic and often severe viral infections in 4 patients with interferon-γ receptor deficiency and mycobacterial d...

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Detalles Bibliográficos
Autores principales: Dorman, Susan E., Uzel, Gulbu, Roesler, Joachim, Bradley, John S., Bastian, John, Billman, Glenn, King, Susan, Filie, Armando, Schermerhorn, James, Holland, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby, Inc. 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095028/
https://www.ncbi.nlm.nih.gov/pubmed/10547254
http://dx.doi.org/10.1016/S0022-3476(99)70064-8
Descripción
Sumario:Interferon-γ receptor deficiency is a recently described immunodeficiency that is associated with onset of severe mycobacterial infections in childhood. We describe the occurrence of symptomatic and often severe viral infections in 4 patients with interferon-γ receptor deficiency and mycobacterial disease. The viral pathogens included herpes viruses, parainfluenza virus type 3, and respiratory syncytial virus. We conclude that patients with interferon-γ receptor deficiency and mycobacterial disease have increased susceptibility to some viral pathogens. (J Pediatr 1999;135:640-3)