The role of blood microfilters in clinical practice

Blood filters have been available since the 1930s. In this review we evaluate the role of microaggregate filters (MF) in certain transfusion complications, namely non-haemolytic febrile transfusion reactions (NHFTR), pulmonary injury, thrombocytopenia, fibronectin depletion and histamine release. We...

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Detalles Bibliográficos
Autores principales: Kapadia, F., Valentine, S., Smith, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1992
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095239/
https://www.ncbi.nlm.nih.gov/pubmed/1527254
http://dx.doi.org/10.1007/BF01706469
Descripción
Sumario:Blood filters have been available since the 1930s. In this review we evaluate the role of microaggregate filters (MF) in certain transfusion complications, namely non-haemolytic febrile transfusion reactions (NHFTR), pulmonary injury, thrombocytopenia, fibronectin depletion and histamine release. We review the latest generation of leucocyte depleting filters and discuss their role in preventing alloimmunisation, immunosuppression and CMV transmission. Finally, we provide a rationale for the role of blood microfiltration in the present day practice of intensive care medicine.

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