The role of blood microfilters in clinical practice

Blood filters have been available since the 1930s. In this review we evaluate the role of microaggregate filters (MF) in certain transfusion complications, namely non-haemolytic febrile transfusion reactions (NHFTR), pulmonary injury, thrombocytopenia, fibronectin depletion and histamine release. We...

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Detalles Bibliográficos
Autores principales: Kapadia, F., Valentine, S., Smith, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1992
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095239/
https://www.ncbi.nlm.nih.gov/pubmed/1527254
http://dx.doi.org/10.1007/BF01706469
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author Kapadia, F.
Valentine, S.
Smith, G.
author_facet Kapadia, F.
Valentine, S.
Smith, G.
author_sort Kapadia, F.
collection PubMed
description Blood filters have been available since the 1930s. In this review we evaluate the role of microaggregate filters (MF) in certain transfusion complications, namely non-haemolytic febrile transfusion reactions (NHFTR), pulmonary injury, thrombocytopenia, fibronectin depletion and histamine release. We review the latest generation of leucocyte depleting filters and discuss their role in preventing alloimmunisation, immunosuppression and CMV transmission. Finally, we provide a rationale for the role of blood microfiltration in the present day practice of intensive care medicine.
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spelling pubmed-70952392020-03-26 The role of blood microfilters in clinical practice Kapadia, F. Valentine, S. Smith, G. Intensive Care Med Review Article Blood filters have been available since the 1930s. In this review we evaluate the role of microaggregate filters (MF) in certain transfusion complications, namely non-haemolytic febrile transfusion reactions (NHFTR), pulmonary injury, thrombocytopenia, fibronectin depletion and histamine release. We review the latest generation of leucocyte depleting filters and discuss their role in preventing alloimmunisation, immunosuppression and CMV transmission. Finally, we provide a rationale for the role of blood microfiltration in the present day practice of intensive care medicine. Springer-Verlag 1992 /pmc/articles/PMC7095239/ /pubmed/1527254 http://dx.doi.org/10.1007/BF01706469 Text en © Springer-Verlag 1992 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Kapadia, F.
Valentine, S.
Smith, G.
The role of blood microfilters in clinical practice
title The role of blood microfilters in clinical practice
title_full The role of blood microfilters in clinical practice
title_fullStr The role of blood microfilters in clinical practice
title_full_unstemmed The role of blood microfilters in clinical practice
title_short The role of blood microfilters in clinical practice
title_sort role of blood microfilters in clinical practice
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095239/
https://www.ncbi.nlm.nih.gov/pubmed/1527254
http://dx.doi.org/10.1007/BF01706469
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