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Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten

Cerebrospinal fluid (CSF) analysis is of utmost importance to establish an early diagnosis of central nervous system (CNS) infections and to start appropriate therapy. The CSF white cell count, lactate concentration and total protein levels are usually available very quickly even from non-specialize...

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Autores principales: Süssmuth, S.D., Brettschneider, J., Spreer, A., Wick, M., Jesse, S., Lewerenz, J., Otto, M., Tumani, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095826/
https://www.ncbi.nlm.nih.gov/pubmed/23371378
http://dx.doi.org/10.1007/s00115-012-3701-8
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author Süssmuth, S.D.
Brettschneider, J.
Spreer, A.
Wick, M.
Jesse, S.
Lewerenz, J.
Otto, M.
Tumani, H.
author_facet Süssmuth, S.D.
Brettschneider, J.
Spreer, A.
Wick, M.
Jesse, S.
Lewerenz, J.
Otto, M.
Tumani, H.
author_sort Süssmuth, S.D.
collection PubMed
description Cerebrospinal fluid (CSF) analysis is of utmost importance to establish an early diagnosis of central nervous system (CNS) infections and to start appropriate therapy. The CSF white cell count, lactate concentration and total protein levels are usually available very quickly even from non-specialized laboratories and the combination of these parameters often provides sufficient information for decision-making in emergency cases. It is, however, not always possible to identify the underlying infective agent despite further CSF analyses, such as bacterial and fungal staining, evaluation of the blood-CSF barrier function, intrathecal immunoglobulin synthesis and oligoclonal IgG bands. Therefore, close communication between the laboratory and the clinician is an important prerequisite to specify additional pathogen-related diagnostic measures for successful confirmation of the diagnosis.
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spelling pubmed-70958262020-03-26 Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten Süssmuth, S.D. Brettschneider, J. Spreer, A. Wick, M. Jesse, S. Lewerenz, J. Otto, M. Tumani, H. Nervenarzt CME Zertifizierte Fortbildung Cerebrospinal fluid (CSF) analysis is of utmost importance to establish an early diagnosis of central nervous system (CNS) infections and to start appropriate therapy. The CSF white cell count, lactate concentration and total protein levels are usually available very quickly even from non-specialized laboratories and the combination of these parameters often provides sufficient information for decision-making in emergency cases. It is, however, not always possible to identify the underlying infective agent despite further CSF analyses, such as bacterial and fungal staining, evaluation of the blood-CSF barrier function, intrathecal immunoglobulin synthesis and oligoclonal IgG bands. Therefore, close communication between the laboratory and the clinician is an important prerequisite to specify additional pathogen-related diagnostic measures for successful confirmation of the diagnosis. Springer-Verlag 2013-02-02 2013 /pmc/articles/PMC7095826/ /pubmed/23371378 http://dx.doi.org/10.1007/s00115-012-3701-8 Text en © Springer-Verlag Berlin Heidelberg 2013 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle CME Zertifizierte Fortbildung
Süssmuth, S.D.
Brettschneider, J.
Spreer, A.
Wick, M.
Jesse, S.
Lewerenz, J.
Otto, M.
Tumani, H.
Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten
title Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten
title_full Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten
title_fullStr Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten
title_full_unstemmed Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten
title_short Aktuelle Liquordiagnostik bei erregerbedingten Krankheiten
title_sort aktuelle liquordiagnostik bei erregerbedingten krankheiten
topic CME Zertifizierte Fortbildung
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095826/
https://www.ncbi.nlm.nih.gov/pubmed/23371378
http://dx.doi.org/10.1007/s00115-012-3701-8
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