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Pegylated interferon-α protects type 1 pneumocytes against SARS coronavirus infection in macaques

The primary cause of severe acute respiratory syndrome (SARS) is a newly discovered coronavirus(1,2,3,4,5,6,7). Replication of this SARS coronavirus (SCV) occurs mainly in the lower respiratory tract, and causes diffuse alveolar damage(2,7,8). Lack of understanding of the pathogenesis of SARS has pr...

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Detalles Bibliográficos
Autores principales: Haagmans, Bart L, Kuiken, Thijs, Martina, Byron E, Fouchier, Ron A M, Rimmelzwaan, Guus F, van Amerongen, Geert, van Riel, Debby, de Jong, Ton, Itamura, Shigeyuki, Chan, Kwok-Hung, Tashiro, Masato, Osterhaus, Albert D M E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095986/
https://www.ncbi.nlm.nih.gov/pubmed/14981511
http://dx.doi.org/10.1038/nm1001