Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer

The factors that influence nanoparticle fate in vivo following systemic delivery remain an area of intense interest. Of particular interest is whether labeling with a cancer-specific antibody ligand (“active targeting”) is superior to its unlabeled counterpart (“passive targeting”). Using models of...

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Detalles Bibliográficos
Autores principales: Korangath, Preethi, Barnett, James D., Sharma, Anirudh, Henderson, Elizabeth T., Stewart, Jacqueline, Yu, Shu-Han, Kandala, Sri Kamal, Yang, Chun-Ting, Caserto, Julia S., Hedayati, Mohammad, Armstrong, Todd D., Jaffee, Elizabeth, Gruettner, Cordula, Zhou, Xian C., Fu, Wei, Hu, Chen, Sukumar, Saraswati, Simons, Brian W., Ivkov, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096167/
https://www.ncbi.nlm.nih.gov/pubmed/32232146
http://dx.doi.org/10.1126/sciadv.aay1601

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