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A new algorithm to convert a normal antibody into the corresponding catalytic antibody
Over thousands of monoclonal antibodies (mAbs) have been produced so far, and it would be valuable if these mAbs could be directly converted into catalytic antibodies. We have designed a system to realize the above concept by deleting Pro(95), a highly conserved residue in CDR-3 of the antibody ligh...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096177/ https://www.ncbi.nlm.nih.gov/pubmed/32232151 http://dx.doi.org/10.1126/sciadv.aay6441 |