Cargando…

Prevalence and prevention of brucellosis in cattle in Lebanon

BACKGROUND AND AIM: Brucellosis is a zoonotic disease caused by the bacterium of the genus Brucella. This disease is present worldwide, especially in developing and underdeveloped countries, where it is endemic. This first-of-its-kind study in Lebanon aimed to assess the prevalence of brucellosis ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Hassan, Hussein, Salami, Ali, Nehme, Nada, Hakeem, Raed Al, Hage, Jeanne El, Awada, Rana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096292/
https://www.ncbi.nlm.nih.gov/pubmed/32255981
http://dx.doi.org/10.14202/vetworld.2020.364-371
_version_ 1783510773946908672
author Hassan, Hussein
Salami, Ali
Nehme, Nada
Hakeem, Raed Al
Hage, Jeanne El
Awada, Rana
author_facet Hassan, Hussein
Salami, Ali
Nehme, Nada
Hakeem, Raed Al
Hage, Jeanne El
Awada, Rana
author_sort Hassan, Hussein
collection PubMed
description BACKGROUND AND AIM: Brucellosis is a zoonotic disease caused by the bacterium of the genus Brucella. This disease is present worldwide, especially in developing and underdeveloped countries, where it is endemic. This first-of-its-kind study in Lebanon aimed to assess the prevalence of brucellosis across the country and to determine the efficacy of a vaccine for reducing losses in herds so that its toll on public health is reduced. MATERIALS AND METHODS: Three hundred and fifty-three blood serum and 261 milk samples were obtained from cows in different areas of Lebanon. The samples were analyzed using serological tests (rose Bengal, milk ring, and indirect enzyme-linked immunosorbent assay [ELISA]) and confirmed with competitive ELISA and polymerase chain reaction. RESULTS: The highest rate of Brucellae was found in the Bekaa region (10%). After vaccination of 5 cows and 13 heifers at different times, the results showed that all the vaccinated animals have developed an immune response to brucellosis 60 days after vaccination. This vaccine can be considered as stable and preventative to protect against brucellosis in animals and thus protect the public from this infection. CONCLUSION: These findings will provide further insight into designing future targeted awareness interventions and adapted policies as efforts toward reducing the prevalence and prevention of brucellosis in cattle in Lebanon.
format Online
Article
Text
id pubmed-7096292
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Veterinary World
record_format MEDLINE/PubMed
spelling pubmed-70962922020-04-01 Prevalence and prevention of brucellosis in cattle in Lebanon Hassan, Hussein Salami, Ali Nehme, Nada Hakeem, Raed Al Hage, Jeanne El Awada, Rana Vet World Research Article BACKGROUND AND AIM: Brucellosis is a zoonotic disease caused by the bacterium of the genus Brucella. This disease is present worldwide, especially in developing and underdeveloped countries, where it is endemic. This first-of-its-kind study in Lebanon aimed to assess the prevalence of brucellosis across the country and to determine the efficacy of a vaccine for reducing losses in herds so that its toll on public health is reduced. MATERIALS AND METHODS: Three hundred and fifty-three blood serum and 261 milk samples were obtained from cows in different areas of Lebanon. The samples were analyzed using serological tests (rose Bengal, milk ring, and indirect enzyme-linked immunosorbent assay [ELISA]) and confirmed with competitive ELISA and polymerase chain reaction. RESULTS: The highest rate of Brucellae was found in the Bekaa region (10%). After vaccination of 5 cows and 13 heifers at different times, the results showed that all the vaccinated animals have developed an immune response to brucellosis 60 days after vaccination. This vaccine can be considered as stable and preventative to protect against brucellosis in animals and thus protect the public from this infection. CONCLUSION: These findings will provide further insight into designing future targeted awareness interventions and adapted policies as efforts toward reducing the prevalence and prevention of brucellosis in cattle in Lebanon. Veterinary World 2020-02 2020-02-27 /pmc/articles/PMC7096292/ /pubmed/32255981 http://dx.doi.org/10.14202/vetworld.2020.364-371 Text en Copyright: © Hassan, et al. http://creativecommons.org/licenses/by/4.0 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hassan, Hussein
Salami, Ali
Nehme, Nada
Hakeem, Raed Al
Hage, Jeanne El
Awada, Rana
Prevalence and prevention of brucellosis in cattle in Lebanon
title Prevalence and prevention of brucellosis in cattle in Lebanon
title_full Prevalence and prevention of brucellosis in cattle in Lebanon
title_fullStr Prevalence and prevention of brucellosis in cattle in Lebanon
title_full_unstemmed Prevalence and prevention of brucellosis in cattle in Lebanon
title_short Prevalence and prevention of brucellosis in cattle in Lebanon
title_sort prevalence and prevention of brucellosis in cattle in lebanon
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096292/
https://www.ncbi.nlm.nih.gov/pubmed/32255981
http://dx.doi.org/10.14202/vetworld.2020.364-371
work_keys_str_mv AT hassanhussein prevalenceandpreventionofbrucellosisincattleinlebanon
AT salamiali prevalenceandpreventionofbrucellosisincattleinlebanon
AT nehmenada prevalenceandpreventionofbrucellosisincattleinlebanon
AT hakeemraedal prevalenceandpreventionofbrucellosisincattleinlebanon
AT hagejeanneel prevalenceandpreventionofbrucellosisincattleinlebanon
AT awadarana prevalenceandpreventionofbrucellosisincattleinlebanon