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Thirdhand smoke: Genotoxicity and carcinogenic potential

Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has bee...

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Autores principales: Hang, Bo, Wang, Pin, Zhao, Yue, Chang, Hang, Mao, Jian-Hua, Snijders, Antoine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096322/
https://www.ncbi.nlm.nih.gov/pubmed/32226932
http://dx.doi.org/10.1016/j.cdtm.2019.08.002
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author Hang, Bo
Wang, Pin
Zhao, Yue
Chang, Hang
Mao, Jian-Hua
Snijders, Antoine M.
author_facet Hang, Bo
Wang, Pin
Zhao, Yue
Chang, Hang
Mao, Jian-Hua
Snijders, Antoine M.
author_sort Hang, Bo
collection PubMed
description Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has been well documented as a risk factor for human cancers, especially lung cancer. However, the concept of THS as a distinct entity that poses health risks for small children has developed only recently and the associations of THS with cancer risk and other chronic diseases are poorly understood due to limited numbers of studies to date. In this perspective, we mainly summarize all published studies on the genotoxicity and carcinogenic potential of THS exposure. These studies begin to fill the knowledge gap in our understanding of cancer risk of THS. Accumulating data from existing and future studies will help reduce the tobacco-related cancer incidence through changes in lifestyle and tobacco control policies.
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spelling pubmed-70963222020-03-27 Thirdhand smoke: Genotoxicity and carcinogenic potential Hang, Bo Wang, Pin Zhao, Yue Chang, Hang Mao, Jian-Hua Snijders, Antoine M. Chronic Dis Transl Med Perspective Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has been well documented as a risk factor for human cancers, especially lung cancer. However, the concept of THS as a distinct entity that poses health risks for small children has developed only recently and the associations of THS with cancer risk and other chronic diseases are poorly understood due to limited numbers of studies to date. In this perspective, we mainly summarize all published studies on the genotoxicity and carcinogenic potential of THS exposure. These studies begin to fill the knowledge gap in our understanding of cancer risk of THS. Accumulating data from existing and future studies will help reduce the tobacco-related cancer incidence through changes in lifestyle and tobacco control policies. Chinese Medical Association 2019-09-26 /pmc/articles/PMC7096322/ /pubmed/32226932 http://dx.doi.org/10.1016/j.cdtm.2019.08.002 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Perspective
Hang, Bo
Wang, Pin
Zhao, Yue
Chang, Hang
Mao, Jian-Hua
Snijders, Antoine M.
Thirdhand smoke: Genotoxicity and carcinogenic potential
title Thirdhand smoke: Genotoxicity and carcinogenic potential
title_full Thirdhand smoke: Genotoxicity and carcinogenic potential
title_fullStr Thirdhand smoke: Genotoxicity and carcinogenic potential
title_full_unstemmed Thirdhand smoke: Genotoxicity and carcinogenic potential
title_short Thirdhand smoke: Genotoxicity and carcinogenic potential
title_sort thirdhand smoke: genotoxicity and carcinogenic potential
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096322/
https://www.ncbi.nlm.nih.gov/pubmed/32226932
http://dx.doi.org/10.1016/j.cdtm.2019.08.002
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