Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Antidepressants demonstrate modest response rates in the treatment of major depressive disorder (MDD). Despite previous genome-wide association studies (GWAS) of antidepressant treatment response, the underlying genetic factors are unknown. Using prescription data in a population and family-based co...

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Detalles Bibliográficos
Autores principales: Wigmore, Eleanor M., Hafferty, Jonathan D., Hall, Lynsey S., Howard, David M., Clarke, Toni-Kim, Fabbri, Chiara, Lewis, Cathryn M., Uher, Rudolf, Navrady, Lauren B., Adams, Mark J., Zeng, Yanni, Campbell, Archie, Gibson, Jude, Thomson, Pippa A., Hayward, Caroline, Smith, Blair H., Hocking, Lynne J., Padmanabhan, Sandosh, Deary, Ian J., Porteous, David J., Mors, Ole, Mattheisen, Manuel, Nicodemus, Kristin K., McIntosh, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096334/
https://www.ncbi.nlm.nih.gov/pubmed/30700811
http://dx.doi.org/10.1038/s41397-019-0067-3

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