Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction

Men and women become infertile with age, but the mechanism of declining male fertility, more specifically, the decrease in in sperm quality, is not well known. Citrate synthase (CS) is a core enzyme of the mitochondrial tricarboxylic acid (TCA) cycle, which directly controls cellular function. Extra...

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Detalles Bibliográficos
Autores principales: Kang, Woojin, Harada, Yuichirou, Yamatoya, Kenji, Kawano, Natsuko, Kanai, Seiya, Miyamoto, Yoshitaka, Nakamura, Akihiro, Miyado, Mami, Hayashi, Yoshiki, Kuroki, Yoko, Saito, Hidekazu, Iwao, Yasuhiro, Umezawa, Akihiro, Miyado, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096335/
https://www.ncbi.nlm.nih.gov/pubmed/31857692
http://dx.doi.org/10.1038/s41374-019-0353-3

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