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Fungal Cell Wall and Methyl-β–Cyclodextrin Synergistically Enhance Paclitaxel Biosynthesis and Secretion in Corylus avellana Cell Suspension Culture

Paclitaxel is the top-selling chemotherapeutic drug used for the treatment of lung, ovarian and breast cancer as well as Kaposi’s sarcoma. Cell suspension culture (CSC) of Corylus avellana has been addressed as a promising alternative for producing paclitaxel. In this study, endophytic fungus strain...

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Detalles Bibliográficos
Autores principales: Farhadi, Siamak, Moieni, Ahmad, Safaie, Naser, Sabet, Mohammad Sadegh, Salehi, Mina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096423/
https://www.ncbi.nlm.nih.gov/pubmed/32214149
http://dx.doi.org/10.1038/s41598-020-62196-4