Combined deletions of IHH and NHEJ1 cause chondrodystrophy and embryonic lethality in the Creeper chicken

The Creeper (Cp) chicken is characterized by chondrodystrophy in Cp/+ heterozygotes and embryonic lethality in Cp/Cp homozygotes. However, the genes underlying the phenotypes have not been fully known. Here, we show that a 25 kb deletion on chromosome 7, which contains the Indian hedgehog (IHH) and...

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Detalles Bibliográficos
Autores principales: Kinoshita, Keiji, Suzuki, Takayuki, Koike, Manabu, Nishida, Chizuko, Koike, Aki, Nunome, Mitsuo, Uemura, Takeo, Ichiyanagi, Kenji, Matsuda, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096424/
https://www.ncbi.nlm.nih.gov/pubmed/32214226
http://dx.doi.org/10.1038/s42003-020-0870-z

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