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Generating high quality libraries for DIA MS with empirically corrected peptide predictions
Data-independent acquisition approaches typically rely on experiment-specific spectrum libraries, requiring offline fractionation and tens to hundreds of injections. We demonstrate a library generation workflow that leverages fragmentation and retention time prediction to build libraries containing...
Autores principales: | Searle, Brian C., Swearingen, Kristian E., Barnes, Christopher A., Schmidt, Tobias, Gessulat, Siegfried, Küster, Bernhard, Wilhelm, Mathias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096433/ https://www.ncbi.nlm.nih.gov/pubmed/32214105 http://dx.doi.org/10.1038/s41467-020-15346-1 |
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