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Suppression of NLRP3 Inflammasome by Erythropoietin via the EPOR/JAK2/STAT3 Pathway Contributes to Attenuation of Acute Lung Injury in Mice

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and devastating clinical disorders with high mortality and no specific therapy. An excessive inflammatory response results in the progression of ALI/ARDS, and the NLRP3 inflammasome is a key participant in inflammation...

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Detalles Bibliográficos
Autores principales: Cao, Fei, Tian, Xinyi, Li, Zhongwang, Lv, Ya, Han, Jun, Zhuang, Rong, Cheng, Bihuan, Gong, Yuqiang, Ying, Binyu, Jin, Shengwei, Gao, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096553/
https://www.ncbi.nlm.nih.gov/pubmed/32265704
http://dx.doi.org/10.3389/fphar.2020.00306