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Plasma disposition of gabapentin after the intragastric administration of escalating doses to adult horses

BACKGROUND: In humans, gabapentin an analgesic, undergoes non‐proportional pharmacokinetics which can alter efficacy. No information exists on the pharmacokinetics of dosages >20 mg/kg, escalating dosages or dose proportionality of gabapentin in horses. HYPOTHESIS AND OBJECTIVES: Gabapentin expos...

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Detalles Bibliográficos
Autores principales: Gold, Jenifer R., Grubb, Tamara L., Green, Stephen, Cox, Sherry, Villarino, Nicolas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096665/
https://www.ncbi.nlm.nih.gov/pubmed/32034928
http://dx.doi.org/10.1111/jvim.15724

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