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Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020

The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3–23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a s...

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Autores principales: Haveri, Anu, Smura, Teemu, Kuivanen, Suvi, Österlund, Pamela, Hepojoki, Jussi, Ikonen, Niina, Pitkäpaasi, Marjaana, Blomqvist, Soile, Rönkkö, Esa, Kantele, Anu, Strandin, Tomas, Kallio-Kokko, Hannimari, Mannonen, Laura, Lappalainen, Maija, Broas, Markku, Jiang, Miao, Siira, Lotta, Salminen, Mika, Puumalainen, Taneli, Sane, Jussi, Melin, Merit, Vapalahti, Olli, Savolainen-Kopra, Carita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096774/
https://www.ncbi.nlm.nih.gov/pubmed/32209163
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.11.2000266
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author Haveri, Anu
Smura, Teemu
Kuivanen, Suvi
Österlund, Pamela
Hepojoki, Jussi
Ikonen, Niina
Pitkäpaasi, Marjaana
Blomqvist, Soile
Rönkkö, Esa
Kantele, Anu
Strandin, Tomas
Kallio-Kokko, Hannimari
Mannonen, Laura
Lappalainen, Maija
Broas, Markku
Jiang, Miao
Siira, Lotta
Salminen, Mika
Puumalainen, Taneli
Sane, Jussi
Melin, Merit
Vapalahti, Olli
Savolainen-Kopra, Carita
author_facet Haveri, Anu
Smura, Teemu
Kuivanen, Suvi
Österlund, Pamela
Hepojoki, Jussi
Ikonen, Niina
Pitkäpaasi, Marjaana
Blomqvist, Soile
Rönkkö, Esa
Kantele, Anu
Strandin, Tomas
Kallio-Kokko, Hannimari
Mannonen, Laura
Lappalainen, Maija
Broas, Markku
Jiang, Miao
Siira, Lotta
Salminen, Mika
Puumalainen, Taneli
Sane, Jussi
Melin, Merit
Vapalahti, Olli
Savolainen-Kopra, Carita
author_sort Haveri, Anu
collection PubMed
description The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3–23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins.
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spelling pubmed-70967742020-03-26 Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020 Haveri, Anu Smura, Teemu Kuivanen, Suvi Österlund, Pamela Hepojoki, Jussi Ikonen, Niina Pitkäpaasi, Marjaana Blomqvist, Soile Rönkkö, Esa Kantele, Anu Strandin, Tomas Kallio-Kokko, Hannimari Mannonen, Laura Lappalainen, Maija Broas, Markku Jiang, Miao Siira, Lotta Salminen, Mika Puumalainen, Taneli Sane, Jussi Melin, Merit Vapalahti, Olli Savolainen-Kopra, Carita Euro Surveill Rapid Communication The first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3–23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins. European Centre for Disease Prevention and Control (ECDC) 2020-03-19 /pmc/articles/PMC7096774/ /pubmed/32209163 http://dx.doi.org/10.2807/1560-7917.ES.2020.25.11.2000266 Text en This article is copyright of the authors or their affiliated institutions, 2020. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Haveri, Anu
Smura, Teemu
Kuivanen, Suvi
Österlund, Pamela
Hepojoki, Jussi
Ikonen, Niina
Pitkäpaasi, Marjaana
Blomqvist, Soile
Rönkkö, Esa
Kantele, Anu
Strandin, Tomas
Kallio-Kokko, Hannimari
Mannonen, Laura
Lappalainen, Maija
Broas, Markku
Jiang, Miao
Siira, Lotta
Salminen, Mika
Puumalainen, Taneli
Sane, Jussi
Melin, Merit
Vapalahti, Olli
Savolainen-Kopra, Carita
Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
title Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
title_full Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
title_fullStr Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
title_full_unstemmed Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
title_short Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
title_sort serological and molecular findings during sars-cov-2 infection: the first case study in finland, january to february 2020
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096774/
https://www.ncbi.nlm.nih.gov/pubmed/32209163
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.11.2000266
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