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From empiricism to rational design: a personal perspective of the evolution of vaccine development
Vaccination, which is the most effective medical intervention that has ever been introduced, originated from the observation that individuals who survived a plague or smallpox would not get the disease twice. To mimic the protective effects of natural infection, Jenner — and later Pasteur — inoculat...
Autores principales: | De Gregorio, Ennio, Rappuoli, Rino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096907/ https://www.ncbi.nlm.nih.gov/pubmed/24925139 http://dx.doi.org/10.1038/nri3694 |
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