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Insights into SARS-CoV transcription and replication from the structure of the nsp7–nsp8 hexadecamer

Coronavirus replication and transcription machinery involves multiple virus-encoded nonstructural proteins (nsp). We report the crystal structure of the hexadecameric nsp7–nsp8 supercomplex from the severe acute respiratory syndrome coronavirus at 2.4-Å resolution. nsp8 has a novel 'golf-club&#...

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Detalles Bibliográficos
Autores principales:	Zhai, Yujia, Sun, Fei, Li, Xuemei, Pang, Hai, Xu, Xiaoling, Bartlam, Mark, Rao, Zihe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096913/ https://www.ncbi.nlm.nih.gov/pubmed/16228002 http://dx.doi.org/10.1038/nsmb999

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