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Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection
Severe acute respiratory syndrome (SARS) is caused by infection of a previously undescribed coronavirus (CoV). L-SIGN, encoded by CLEC4M (also known as CD209L), is a SARS-CoV binding receptor that has polymorphism in its extracellular neck region encoded by the tandem repeat domain in exon 4. Our ge...
Autores principales: | Chan, Vera S F, Chan, Kelvin Y K, Chen, Yongxiong, Poon, Leo L M, Cheung, Annie N Y, Zheng, Bojian, Chan, Kwok-Hung, Mak, William, Ngan, Hextan Y S, Xu, Xiaoning, Screaton, Gavin, Tam, Paul K H, Austyn, Jonathan M, Chan, Li-Chong, Yip, Shea-Ping, Peiris, Malik, Khoo, Ui-Soon, Lin, Chen-Lung S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097088/ https://www.ncbi.nlm.nih.gov/pubmed/16369534 http://dx.doi.org/10.1038/ng1698 |
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