Challenges and approaches for the development of safer immunomodulatory biologics

Immunomodulatory biologics, which render their therapeutic effects by modulating or harnessing immune responses, have proven their therapeutic utility in several complex conditions including cancer and autoimmune diseases. However, unwanted adverse reactions — including serious infections, malignanc...

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Detalles Bibliográficos
Autores principales: Sathish, Jean G., Sethu, Swaminathan, Bielsky, Marie-Christine, de Haan, Lolke, French, Neil S., Govindappa, Karthik, Green, James, Griffiths, Christopher E. M., Holgate, Stephen, Jones, David, Kimber, Ian, Moggs, Jonathan, Naisbitt, Dean J., Pirmohamed, Munir, Reichmann, Gabriele, Sims, Jennifer, Subramanyam, Meena, Todd, Marque D., Van Der Laan, Jan Willem, Weaver, Richard J., Park, B. Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097261/
https://www.ncbi.nlm.nih.gov/pubmed/23535934
http://dx.doi.org/10.1038/nrd3974

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