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Aptamers as therapeutics

Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to bind a wide range of biomedically relevant proteins with affinities and specificities that are comparable to antibodies. Aptamers exhibit significant advantages relative to protein therapeutics in terms of size,...

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Detalles Bibliográficos
Autores principales: Keefe, Anthony D., Pai, Supriya, Ellington, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097324/
https://www.ncbi.nlm.nih.gov/pubmed/20592747
http://dx.doi.org/10.1038/nrd3141

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