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Aptamers as therapeutics
Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to bind a wide range of biomedically relevant proteins with affinities and specificities that are comparable to antibodies. Aptamers exhibit significant advantages relative to protein therapeutics in terms of size,...
Autores principales: | Keefe, Anthony D., Pai, Supriya, Ellington, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097324/ https://www.ncbi.nlm.nih.gov/pubmed/20592747 http://dx.doi.org/10.1038/nrd3141 |
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