Cargando…

Pathogen profiling for disease management and surveillance

The usefulness of rapid pathogen genotyping is widely recognized, but its effective interpretation and application requires integration into clinical and public health decision-making. How can pathogen genotyping data best be translated to inform disease management and surveillance? Pathogen profili...

Descripción completa

Detalles Bibliográficos
Autores principales: Sintchenko, Vitali, Iredell, Jonathan R., Gilbert, Gwendolyn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097369/
https://www.ncbi.nlm.nih.gov/pubmed/17487146
http://dx.doi.org/10.1038/nrmicro1656
Descripción
Sumario:The usefulness of rapid pathogen genotyping is widely recognized, but its effective interpretation and application requires integration into clinical and public health decision-making. How can pathogen genotyping data best be translated to inform disease management and surveillance? Pathogen profiling integrates microbial genomics data into communicable disease control by consolidating phenotypic identity-based methods with DNA microarrays, proteomics, metabolomics and sequence-based typing. Sharing data on pathogen profiles should facilitate our understanding of transmission patterns and the dynamics of epidemics. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/nrmicro1656) contains supplementary material, which is available to authorized users.