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Pathogenic epitopes, heterologous immunity and vaccine design
Substantial research has been directed towards the development of a new generation of vaccines that are based on the inclusion of immunogenic epitopes in recombinant vectors. Here we examine the evidence that under certain conditions immunogenic epitopes can do more harm than good and might therefor...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097378/ https://www.ncbi.nlm.nih.gov/pubmed/17558423 http://dx.doi.org/10.1038/nrmicro1709 |