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Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ?

In 2012 a new viral emergent human disease appeared in the Middle East. This entity was named MERS for’ Middle East respiratory syndrome’. By January 9, 2014, the disease had already struck 178 persons of whom 75 died from respiratory failure and diarrhoea. As the new disease was very similar to the...

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Autor principal: Chastel, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097389/
https://www.ncbi.nlm.nih.gov/pubmed/24532303
http://dx.doi.org/10.1007/s13149-014-0333-1
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author Chastel, C.
author_facet Chastel, C.
author_sort Chastel, C.
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description In 2012 a new viral emergent human disease appeared in the Middle East. This entity was named MERS for’ Middle East respiratory syndrome’. By January 9, 2014, the disease had already struck 178 persons of whom 75 died from respiratory failure and diarrhoea. As the new disease was very similar to the deadly SARS (2002–2003) and since it was provoked by a Betacoronavirus, chiroptera were first suspected to be at the origin of this infection. Morever, recent studies performed in Saudi Arabia showed that one individual of the bat Taphozous perforatus harbored a short nucleotide segment identical to the homologous segment present in the viral strain isolated from the index-case of the epidemic. In addition, many strains of Betacoronavirus more or less related to those responsible for the MERS disease in man have been isolated from bats in Africa, Asia and Europe. However, another hypothesis was simultaneously proposed incriminating dromedary (Camelus dromedarius L.) as a likely actor in the transmission to human beings of the disease.We then reviewed data relative to other viral zoonosis in which dromedary was possibly implicated. This led to the provisional conclusion that this large mammal might play a role in the dissemination of the MERS-COV, the etiologic agent of the disease. This is based on epidemiological data and results of several serological surveys in animals.
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spelling pubmed-70973892020-03-26 Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ? Chastel, C. Bull Soc Pathol Exot Éditorial / Editorial In 2012 a new viral emergent human disease appeared in the Middle East. This entity was named MERS for’ Middle East respiratory syndrome’. By January 9, 2014, the disease had already struck 178 persons of whom 75 died from respiratory failure and diarrhoea. As the new disease was very similar to the deadly SARS (2002–2003) and since it was provoked by a Betacoronavirus, chiroptera were first suspected to be at the origin of this infection. Morever, recent studies performed in Saudi Arabia showed that one individual of the bat Taphozous perforatus harbored a short nucleotide segment identical to the homologous segment present in the viral strain isolated from the index-case of the epidemic. In addition, many strains of Betacoronavirus more or less related to those responsible for the MERS disease in man have been isolated from bats in Africa, Asia and Europe. However, another hypothesis was simultaneously proposed incriminating dromedary (Camelus dromedarius L.) as a likely actor in the transmission to human beings of the disease.We then reviewed data relative to other viral zoonosis in which dromedary was possibly implicated. This led to the provisional conclusion that this large mammal might play a role in the dissemination of the MERS-COV, the etiologic agent of the disease. This is based on epidemiological data and results of several serological surveys in animals. Springer Paris 2014-02-15 2014 /pmc/articles/PMC7097389/ /pubmed/24532303 http://dx.doi.org/10.1007/s13149-014-0333-1 Text en © Springer-Verlag France 2014 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Éditorial / Editorial
Chastel, C.
Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ?
title Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ?
title_full Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ?
title_fullStr Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ?
title_full_unstemmed Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ?
title_short Le « syndrome respiratoire du Moyen-Orient » (MERS) : qui est responsable, les chauves-souris ou le dromadaire ?
title_sort le « syndrome respiratoire du moyen-orient » (mers) : qui est responsable, les chauves-souris ou le dromadaire ?
topic Éditorial / Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097389/
https://www.ncbi.nlm.nih.gov/pubmed/24532303
http://dx.doi.org/10.1007/s13149-014-0333-1
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