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Emerging biomedical applications of synthetic biology

Synthetic biology aims to create functional devices, systems and organisms with novel and useful functions on the basis of catalogued and standardized biological building blocks. Although they were initially constructed to elucidate the dynamics of simple processes, designed devices now contribute t...

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Detalles Bibliográficos
Autores principales: Weber, Wilfried, Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097403/
https://www.ncbi.nlm.nih.gov/pubmed/22124480
http://dx.doi.org/10.1038/nrg3094
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author Weber, Wilfried
Fussenegger, Martin
author_facet Weber, Wilfried
Fussenegger, Martin
author_sort Weber, Wilfried
collection PubMed
description Synthetic biology aims to create functional devices, systems and organisms with novel and useful functions on the basis of catalogued and standardized biological building blocks. Although they were initially constructed to elucidate the dynamics of simple processes, designed devices now contribute to the understanding of disease mechanisms, provide novel diagnostic tools, enable economic production of therapeutics and allow the design of novel strategies for the treatment of cancer, immune diseases and metabolic disorders, such as diabetes and gout, as well as a range of infectious diseases. In this Review, we cover the impact and potential of synthetic biology for biomedical applications.
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spelling pubmed-70974032020-03-26 Emerging biomedical applications of synthetic biology Weber, Wilfried Fussenegger, Martin Nat Rev Genet Article Synthetic biology aims to create functional devices, systems and organisms with novel and useful functions on the basis of catalogued and standardized biological building blocks. Although they were initially constructed to elucidate the dynamics of simple processes, designed devices now contribute to the understanding of disease mechanisms, provide novel diagnostic tools, enable economic production of therapeutics and allow the design of novel strategies for the treatment of cancer, immune diseases and metabolic disorders, such as diabetes and gout, as well as a range of infectious diseases. In this Review, we cover the impact and potential of synthetic biology for biomedical applications. Nature Publishing Group UK 2011-11-29 2012 /pmc/articles/PMC7097403/ /pubmed/22124480 http://dx.doi.org/10.1038/nrg3094 Text en © Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. 2011 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Weber, Wilfried
Fussenegger, Martin
Emerging biomedical applications of synthetic biology
title Emerging biomedical applications of synthetic biology
title_full Emerging biomedical applications of synthetic biology
title_fullStr Emerging biomedical applications of synthetic biology
title_full_unstemmed Emerging biomedical applications of synthetic biology
title_short Emerging biomedical applications of synthetic biology
title_sort emerging biomedical applications of synthetic biology
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097403/
https://www.ncbi.nlm.nih.gov/pubmed/22124480
http://dx.doi.org/10.1038/nrg3094
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