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Engineering passive immunity in transgenic mice secreting virus-neutralizing antibodies in milk
Protection against enteric infections can be provided by the oral administration of pathogen-neutralizing antibodies. To provide passive immunity, 18 lines of transgenic mice secreting a recombinant monoclonal antibody (Mab) neutralizing transmissible gastroenteritis coronavirus (TGEV) into the milk...
Autores principales: | Castilla, Joaquin, Pintado, Belén, Sola, Isabel, Sánchez-Morgado, José M., Enjuanes, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097410/ https://www.ncbi.nlm.nih.gov/pubmed/9555725 http://dx.doi.org/10.1038/nbt0498-349 |
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