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HCV NS4B targets Scribble for proteasome-mediated degradation to facilitate cell transformation
Hepatitis C virus (HCV) nonstructural protein 4B (NS4B) is a multi-transmembrane protein, but little is known about how NS4B contributes to HCV replication and tumorigenesis. Its C-terminal domain (CTD) has been shown to associate with intracellular membrane, and we have previously shown that NS4B C...
Autores principales: | Hu, Bo, Li, Shanshan, Zhang, Zhanfeng, Xie, Shenggao, Hu, Yuqian, Huang, Xianzhang, Zheng, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097421/ https://www.ncbi.nlm.nih.gov/pubmed/27315218 http://dx.doi.org/10.1007/s13277-016-5100-4 |
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