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HCV NS4B targets Scribble for proteasome-mediated degradation to facilitate cell transformation

Hepatitis C virus (HCV) nonstructural protein 4B (NS4B) is a multi-transmembrane protein, but little is known about how NS4B contributes to HCV replication and tumorigenesis. Its C-terminal domain (CTD) has been shown to associate with intracellular membrane, and we have previously shown that NS4B C...

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Detalles Bibliográficos
Autores principales: Hu, Bo, Li, Shanshan, Zhang, Zhanfeng, Xie, Shenggao, Hu, Yuqian, Huang, Xianzhang, Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097421/
https://www.ncbi.nlm.nih.gov/pubmed/27315218
http://dx.doi.org/10.1007/s13277-016-5100-4

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