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A High Capacity Microbial Screen for Inhibitors of Human Rhinovirus Protease 3C

We have developed a high capacity screen for compounds that inhibit the 3C protease of human rhinovirus–1b. The assay uses a recombinant strain of Escherichia coli expressing both the protease and a tetracycline resistance–conferring protein modified to contain the minimal protease cleavage site. Cu...

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Detalles Bibliográficos
Autores principales: McCall, J. Owen, Kadam, Sunil, Katz, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097487/
https://www.ncbi.nlm.nih.gov/pubmed/7765405
http://dx.doi.org/10.1038/nbt1094-1012