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A High Capacity Microbial Screen for Inhibitors of Human Rhinovirus Protease 3C
We have developed a high capacity screen for compounds that inhibit the 3C protease of human rhinovirus–1b. The assay uses a recombinant strain of Escherichia coli expressing both the protease and a tetracycline resistance–conferring protein modified to contain the minimal protease cleavage site. Cu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
1994
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097487/ https://www.ncbi.nlm.nih.gov/pubmed/7765405 http://dx.doi.org/10.1038/nbt1094-1012 |