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High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a common cause of liver disease worldwide and is a growing epidemic. A high ratio of omega-6 fatty acids to omega-3 fatty acids in the diet has been implicated in the development of NAFLD. However, the inflicted cellular pathology remains unkn...

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Detalles Bibliográficos
Autores principales: Ghazali, Reem, Mehta, Kosha J, Bligh, SW Annie, Tewfik, Ihab, Clemens, Dahn, Patel, Vinood B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097500/
https://www.ncbi.nlm.nih.gov/pubmed/32231762
http://dx.doi.org/10.4254/wjh.v12.i3.84