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Wild-Type IDH1 and Mutant IDH1 Opposingly Regulate Podoplanin Expression in Glioma()()
Isocitrate dehydrogenase (IDH) mutations occur frequently in lower-grade gliomas, which result in genome-wide epigenetic alterations. The wild-type IDH1 is reported to participate in lipid biosynthesis and amino acid metabolism, but its role in tumorigenesis is still unclear. In this study, the expr...
Autores principales: | Sun, Chao, Xiao, Liming, Zhao, Yuanlin, Shi, Jiankuan, Yuan, Yuan, Gu, Yu, Zhang, Feng, Gao, Xing, Yang, Ying, Yang, Risheng, Qin, Junhui, Zhang, Jin, Wang, Chao, Wang, Yingmei, Wang, Zhe, Hu, Peizhen, Chang, Ting, Wang, Liang, Wang, Gang, Chen, Huangtao, Li, Zhuyi, Ye, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097522/ https://www.ncbi.nlm.nih.gov/pubmed/32208352 http://dx.doi.org/10.1016/j.tranon.2020.100758 |
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