Entry of viruses through the epithelial barrier: pathogenic trickery

Mucosal surfaces — such as the lining of the gut or the reproductive tract — are the main point of entry for viruses into the body. As such, almost all viruses interact with epithelial cells, and make use of the normal epithelial signalling and trafficking pathways of the host cell. In addition to p...

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Detalles Bibliográficos
Autores principales: Bomsel, Morgane, Alfsen, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097689/
https://www.ncbi.nlm.nih.gov/pubmed/12511869
http://dx.doi.org/10.1038/nrm1005
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author Bomsel, Morgane
Alfsen, Annette
author_facet Bomsel, Morgane
Alfsen, Annette
author_sort Bomsel, Morgane
collection PubMed
description Mucosal surfaces — such as the lining of the gut or the reproductive tract — are the main point of entry for viruses into the body. As such, almost all viruses interact with epithelial cells, and make use of the normal epithelial signalling and trafficking pathways of the host cell. In addition to protein receptors, carbohydrate chains of proteoglycans and epithelial-membrane glycosphingolipids have emerged as a new class of receptors for viral attachment to the host cell.
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spelling pubmed-70976892020-03-26 Entry of viruses through the epithelial barrier: pathogenic trickery Bomsel, Morgane Alfsen, Annette Nat Rev Mol Cell Biol Article Mucosal surfaces — such as the lining of the gut or the reproductive tract — are the main point of entry for viruses into the body. As such, almost all viruses interact with epithelial cells, and make use of the normal epithelial signalling and trafficking pathways of the host cell. In addition to protein receptors, carbohydrate chains of proteoglycans and epithelial-membrane glycosphingolipids have emerged as a new class of receptors for viral attachment to the host cell. Nature Publishing Group UK 2003 /pmc/articles/PMC7097689/ /pubmed/12511869 http://dx.doi.org/10.1038/nrm1005 Text en © Nature Publishing Group 2003 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Bomsel, Morgane
Alfsen, Annette
Entry of viruses through the epithelial barrier: pathogenic trickery
title Entry of viruses through the epithelial barrier: pathogenic trickery
title_full Entry of viruses through the epithelial barrier: pathogenic trickery
title_fullStr Entry of viruses through the epithelial barrier: pathogenic trickery
title_full_unstemmed Entry of viruses through the epithelial barrier: pathogenic trickery
title_short Entry of viruses through the epithelial barrier: pathogenic trickery
title_sort entry of viruses through the epithelial barrier: pathogenic trickery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097689/
https://www.ncbi.nlm.nih.gov/pubmed/12511869
http://dx.doi.org/10.1038/nrm1005
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AT alfsenannette entryofvirusesthroughtheepithelialbarrierpathogenictrickery

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