Emerging regulation and functions of autophagy

Autophagy maintains cell, tissue and organism homeostasis through degradation. Complex post-translational modulation of the Atg (autophagy-related) proteins adds additional entry points for crosstalk with other cellular processes and helps define cell-type-specific regulations of autophagy. Beyond t...

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Detalles Bibliográficos
Autores principales: Boya, Patricia, Reggiori, Fulvio, Codogno, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097732/
https://www.ncbi.nlm.nih.gov/pubmed/23817233
http://dx.doi.org/10.1038/ncb2788
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author Boya, Patricia
Reggiori, Fulvio
Codogno, Patrice
author_facet Boya, Patricia
Reggiori, Fulvio
Codogno, Patrice
author_sort Boya, Patricia
collection PubMed
description Autophagy maintains cell, tissue and organism homeostasis through degradation. Complex post-translational modulation of the Atg (autophagy-related) proteins adds additional entry points for crosstalk with other cellular processes and helps define cell-type-specific regulations of autophagy. Beyond the simplistic view of a process exclusively dedicated to the turnover of cellular components, recent data have uncovered unexpected functions for autophagy and the autophagy-related genes, such as regulation of metabolism, membrane transport and modulation of host defenses — indicating the novel frontiers lying ahead.
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spelling pubmed-70977322020-03-26 Emerging regulation and functions of autophagy Boya, Patricia Reggiori, Fulvio Codogno, Patrice Nat Cell Biol Article Autophagy maintains cell, tissue and organism homeostasis through degradation. Complex post-translational modulation of the Atg (autophagy-related) proteins adds additional entry points for crosstalk with other cellular processes and helps define cell-type-specific regulations of autophagy. Beyond the simplistic view of a process exclusively dedicated to the turnover of cellular components, recent data have uncovered unexpected functions for autophagy and the autophagy-related genes, such as regulation of metabolism, membrane transport and modulation of host defenses — indicating the novel frontiers lying ahead. Nature Publishing Group UK 2013-07-01 2013 /pmc/articles/PMC7097732/ /pubmed/23817233 http://dx.doi.org/10.1038/ncb2788 Text en © Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. 2013 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Boya, Patricia
Reggiori, Fulvio
Codogno, Patrice
Emerging regulation and functions of autophagy
title Emerging regulation and functions of autophagy
title_full Emerging regulation and functions of autophagy
title_fullStr Emerging regulation and functions of autophagy
title_full_unstemmed Emerging regulation and functions of autophagy
title_short Emerging regulation and functions of autophagy
title_sort emerging regulation and functions of autophagy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097732/
https://www.ncbi.nlm.nih.gov/pubmed/23817233
http://dx.doi.org/10.1038/ncb2788
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AT codognopatrice emergingregulationandfunctionsofautophagy

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