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Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis

BACKGROUND: Medial epicondylitis (ME) is characterized as an overuse injury resulting in pathological alterations of the common flexor tendon at the elbow. Platelet-rich plasma (PRP) has recently become of interest in the treatment of musculoskeletal conditions as an alternative to operative managem...

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Autores principales: Bohlen, Hunter L., Schwartz, Zachary E., Wu, Victor J., Thon, Stephen G., Finley, Zachary J., O’Brien, Michael J., Savoie, Felix H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097873/
https://www.ncbi.nlm.nih.gov/pubmed/32232070
http://dx.doi.org/10.1177/2325967120908952
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author Bohlen, Hunter L.
Schwartz, Zachary E.
Wu, Victor J.
Thon, Stephen G.
Finley, Zachary J.
O’Brien, Michael J.
Savoie, Felix H.
author_facet Bohlen, Hunter L.
Schwartz, Zachary E.
Wu, Victor J.
Thon, Stephen G.
Finley, Zachary J.
O’Brien, Michael J.
Savoie, Felix H.
author_sort Bohlen, Hunter L.
collection PubMed
description BACKGROUND: Medial epicondylitis (ME) is characterized as an overuse injury resulting in pathological alterations of the common flexor tendon at the elbow. Platelet-rich plasma (PRP) has recently become of interest in the treatment of musculoskeletal conditions as an alternative to operative management. PURPOSE: To compare the outcomes of recalcitrant type 1 ME after treatment with either PRP or surgery. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: To compare the 2 methods of treatment, we performed a retrospective review of 33 patients diagnosed with type 1 ME from 2006 to 2016 with a minimum clinical follow-up of 1 year who had failed an initial nonoperative treatment program of injections, medication, topical creams, and/or physical therapy. Overall, 15 patients were treated with a series of 2 leukocyte-rich PRP injections, and 18 patients were treated with surgery. Outcome measures included time to pain-free status, time to full range of motion (ROM), the Mayo Elbow Performance Score (MEPS), and the Oxford Elbow Score (OES). Each patient had at least 1-year follow-up. They were then contacted by telephone to determine final scores at a minimum 2-year follow-up. Unsuccessful outcomes were determined by the Nirschl grading system and failure to reach pain-free status, achieve baseline ROM, or return to previous activity. RESULTS: The mean final follow-up was 3.9 years. A statistically significant improvement was noted in both time to full ROM (42.3 days for PRP vs 96.1 days for surgery; P < .01) and time to pain-free status (56.2 days for PRP vs 108.0 days for surgery; P < .01). Successful outcomes were observed in 80% of patients treated with PRP and 94% of those treated operatively (P = .37). No significant difference was found in return-to-activity rates, overall successful outcomes, MEPS scores, or OES scores. CONCLUSION: In this case series, the use of PRP showed clinically similar outcomes to those of surgery in recalcitrant type 1 ME. PRP can be considered as an alternative to surgery in the treatment of recurrent ME, with an earlier time to full ROM and time to pain-free status compared with surgery.
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spelling pubmed-70978732020-03-30 Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis Bohlen, Hunter L. Schwartz, Zachary E. Wu, Victor J. Thon, Stephen G. Finley, Zachary J. O’Brien, Michael J. Savoie, Felix H. Orthop J Sports Med Article BACKGROUND: Medial epicondylitis (ME) is characterized as an overuse injury resulting in pathological alterations of the common flexor tendon at the elbow. Platelet-rich plasma (PRP) has recently become of interest in the treatment of musculoskeletal conditions as an alternative to operative management. PURPOSE: To compare the outcomes of recalcitrant type 1 ME after treatment with either PRP or surgery. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: To compare the 2 methods of treatment, we performed a retrospective review of 33 patients diagnosed with type 1 ME from 2006 to 2016 with a minimum clinical follow-up of 1 year who had failed an initial nonoperative treatment program of injections, medication, topical creams, and/or physical therapy. Overall, 15 patients were treated with a series of 2 leukocyte-rich PRP injections, and 18 patients were treated with surgery. Outcome measures included time to pain-free status, time to full range of motion (ROM), the Mayo Elbow Performance Score (MEPS), and the Oxford Elbow Score (OES). Each patient had at least 1-year follow-up. They were then contacted by telephone to determine final scores at a minimum 2-year follow-up. Unsuccessful outcomes were determined by the Nirschl grading system and failure to reach pain-free status, achieve baseline ROM, or return to previous activity. RESULTS: The mean final follow-up was 3.9 years. A statistically significant improvement was noted in both time to full ROM (42.3 days for PRP vs 96.1 days for surgery; P < .01) and time to pain-free status (56.2 days for PRP vs 108.0 days for surgery; P < .01). Successful outcomes were observed in 80% of patients treated with PRP and 94% of those treated operatively (P = .37). No significant difference was found in return-to-activity rates, overall successful outcomes, MEPS scores, or OES scores. CONCLUSION: In this case series, the use of PRP showed clinically similar outcomes to those of surgery in recalcitrant type 1 ME. PRP can be considered as an alternative to surgery in the treatment of recurrent ME, with an earlier time to full ROM and time to pain-free status compared with surgery. SAGE Publications 2020-03-25 /pmc/articles/PMC7097873/ /pubmed/32232070 http://dx.doi.org/10.1177/2325967120908952 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
Bohlen, Hunter L.
Schwartz, Zachary E.
Wu, Victor J.
Thon, Stephen G.
Finley, Zachary J.
O’Brien, Michael J.
Savoie, Felix H.
Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis
title Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis
title_full Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis
title_fullStr Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis
title_full_unstemmed Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis
title_short Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis
title_sort platelet-rich plasma is an equal alternative to surgery in the treatment of type 1 medial epicondylitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097873/
https://www.ncbi.nlm.nih.gov/pubmed/32232070
http://dx.doi.org/10.1177/2325967120908952
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