The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation

Background: X chromosome inactivation in mammals is regulated by the non-coding (nc) RNA, Xist, which represses the chromosome from which it is transcribed.  High levels of the N6-methyladenosine (m6A) RNA modification occur within Xist exon I, close to the 5’ end of the transcript, and also further...

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Detalles Bibliográficos
Autores principales: Coker, Heather, Wei, Guifeng, Moindrot, Benoit, Mohammed, Shabaz, Nesterova, Tatyana, Brockdorff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097882/
https://www.ncbi.nlm.nih.gov/pubmed/32258426
http://dx.doi.org/10.12688/wellcomeopenres.15711.1

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