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Fibronectin in the Tumor Microenvironment Activates a TLR4-dependent Inflammatory Response in Lung Cancer Cells

The microenvironment of solid tumors plays an essential role in tumor progression. In lung cancer, the stromal cells produce a fibronectin rich extracellular matrix which is known to contribute to both tumor metastasis and drug resistance. Due to its conformational lability, fibronectin is considera...

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Detalles Bibliográficos
Autores principales: Cho, Christina, Horzempa, Carol, Longo, Christine M., Peters, Donna M., Jones, David M., McKeown-Longo, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097952/
https://www.ncbi.nlm.nih.gov/pubmed/32231714
http://dx.doi.org/10.7150/jca.39771