Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst

[Image: see text] This study describes the solvent and catalyst-free Ugi reaction by way of twin screw extrusion (TSE). Multicomponent chemical synthesis can be converted into a single process without repeated use of solvents through TSE. High synthetic yields are achieved in short reaction times an...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali El-Remaily, Mahmoud Abd El Aleem Ali, Soliman, Ahmed M. M., Elhady, Omar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098038/
https://www.ncbi.nlm.nih.gov/pubmed/32226904
http://dx.doi.org/10.1021/acsomega.0c00369
_version_ 1783511107108864000
author Ali El-Remaily, Mahmoud Abd El Aleem Ali
Soliman, Ahmed M. M.
Elhady, Omar M.
author_facet Ali El-Remaily, Mahmoud Abd El Aleem Ali
Soliman, Ahmed M. M.
Elhady, Omar M.
author_sort Ali El-Remaily, Mahmoud Abd El Aleem Ali
collection PubMed
description [Image: see text] This study describes the solvent and catalyst-free Ugi reaction by way of twin screw extrusion (TSE). Multicomponent chemical synthesis can be converted into a single process without repeated use of solvents through TSE. High synthetic yields are achieved in short reaction times and produced in solvent-free conditions, which lead to a more environmentally friendly process.
format Online
Article
Text
id pubmed-7098038
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-70980382020-03-27 Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst Ali El-Remaily, Mahmoud Abd El Aleem Ali Soliman, Ahmed M. M. Elhady, Omar M. ACS Omega [Image: see text] This study describes the solvent and catalyst-free Ugi reaction by way of twin screw extrusion (TSE). Multicomponent chemical synthesis can be converted into a single process without repeated use of solvents through TSE. High synthetic yields are achieved in short reaction times and produced in solvent-free conditions, which lead to a more environmentally friendly process. American Chemical Society 2020-03-12 /pmc/articles/PMC7098038/ /pubmed/32226904 http://dx.doi.org/10.1021/acsomega.0c00369 Text en Copyright © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Ali El-Remaily, Mahmoud Abd El Aleem Ali
Soliman, Ahmed M. M.
Elhady, Omar M.
Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
title Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
title_full Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
title_fullStr Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
title_full_unstemmed Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
title_short Green Method for the Synthetic Ugi Reaction by Twin Screw Extrusion without a Solvent and Catalyst
title_sort green method for the synthetic ugi reaction by twin screw extrusion without a solvent and catalyst
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098038/
https://www.ncbi.nlm.nih.gov/pubmed/32226904
http://dx.doi.org/10.1021/acsomega.0c00369
work_keys_str_mv AT alielremailymahmoudabdelaleemali greenmethodforthesyntheticugireactionbytwinscrewextrusionwithoutasolventandcatalyst
AT solimanahmedmm greenmethodforthesyntheticugireactionbytwinscrewextrusionwithoutasolventandcatalyst
AT elhadyomarm greenmethodforthesyntheticugireactionbytwinscrewextrusionwithoutasolventandcatalyst

Ejemplares similares