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DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936
BACKGROUND: DNA methylation outlier burden has been suggested as a potential marker of biological age. An outlier is typically defined as DNA methylation levels at any one CpG site that are three times beyond the inter-quartile range from the 25th or 75th percentiles compared to the rest of the popu...
Autores principales: | Seeboth, Anne, McCartney, Daniel L., Wang, Yunzhang, Hillary, Robert F., Stevenson, Anna J., Walker, Rosie M., Campbell, Archie, Evans, Kathryn L., McIntosh, Andrew M., Hägg, Sara, Deary, Ian J., Marioni, Riccardo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098133/ https://www.ncbi.nlm.nih.gov/pubmed/32216821 http://dx.doi.org/10.1186/s13148-020-00838-0 |
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