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Developing a composite outcome measure for frailty prevention trials – rationale, derivation and sample size comparison with other candidate measures
BACKGROUND: Frailty is the loss of ability to withstand a physiological stressor and is associated with multiple adverse outcomes in older people. Trials to prevent or ameliorate frailty are in their infancy. A range of different outcome measures have been proposed, but current measures require eith...
Autores principales: | Witham, Miles D., Wason, James, Dodds, Richard, Sayer, Avan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098153/ https://www.ncbi.nlm.nih.gov/pubmed/32213165 http://dx.doi.org/10.1186/s12877-020-1463-x |
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