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Developing a composite outcome measure for frailty prevention trials – rationale, derivation and sample size comparison with other candidate measures

BACKGROUND: Frailty is the loss of ability to withstand a physiological stressor and is associated with multiple adverse outcomes in older people. Trials to prevent or ameliorate frailty are in their infancy. A range of different outcome measures have been proposed, but current measures require eith...

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Detalles Bibliográficos
Autores principales: Witham, Miles D., Wason, James, Dodds, Richard, Sayer, Avan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098153/
https://www.ncbi.nlm.nih.gov/pubmed/32213165
http://dx.doi.org/10.1186/s12877-020-1463-x

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