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Involvement of p53-dependent apoptosis signal in antitumor effect of Colchicine on human papilloma virus (HPV)-positive human cervical cancer cells

Colchicine, a plant-derived alkaloid with relatively low toxicity on normal human epidermal keratinocytes (HEKn), has selective inhibitory effect on the growth of CaSki (HPV16-positive) and HeLa (HPV18-positive) human cervical cancer cell lines via the induction of apoptosis. Colchicine (2.5, 5.0 an...

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Detalles Bibliográficos
Autores principales:	Yan, Luchun, Huang, Hao, Zhang, Ying, Yuan, Xinrong, Yan, Zhaohua, Cao, Chunyan, Luo, Xiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Therapeutics & Molecular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098170/ https://www.ncbi.nlm.nih.gov/pubmed/32163135 http://dx.doi.org/10.1042/BSR20194065

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