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Assay-Based Differentiation in the Neutralization Profile of Unfractionated Heparin, Enoxaparin, and Fondaparinux by Andexanet Alfa
Andexanet alfa is a recombinant factor Xa decoy protein, designed to reverse bleeding associated with oral anti-Xa agents. Andexanet alfa is also reported to neutralize the effects of heparin-related drugs. This study focused on the neutralization profiles of unfractionated heparin (UFH), enoxaparin...
Autores principales: | Siddiqui, Fakiha, Tafur, Alfonso, Bontekoe, Emily, Iqbal, Omer, Jeske, Walter, Mehrotra, Siddharth, Hoppensteadt, Debra, Ramacciotti, Eduardo, Fareed, Jawed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098205/ https://www.ncbi.nlm.nih.gov/pubmed/31914798 http://dx.doi.org/10.1177/1076029619895120 |
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