Cargando…
Neurorestorative interventions involving bioelectronic implants after spinal cord injury
In the absence of approved treatments to repair damage to the central nervous system, the role of neurosurgeons after spinal cord injury (SCI) often remains confined to spinal cord decompression and vertebral fracture stabilization. However, recent advances in bioelectronic medicine are changing thi...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098222/ https://www.ncbi.nlm.nih.gov/pubmed/32232100 http://dx.doi.org/10.1186/s42234-019-0027-x |
_version_ | 1783511150150811648 |
---|---|
author | Cho, Newton Squair, Jordan W. Bloch, Jocelyne Courtine, Grégoire |
author_facet | Cho, Newton Squair, Jordan W. Bloch, Jocelyne Courtine, Grégoire |
author_sort | Cho, Newton |
collection | PubMed |
description | In the absence of approved treatments to repair damage to the central nervous system, the role of neurosurgeons after spinal cord injury (SCI) often remains confined to spinal cord decompression and vertebral fracture stabilization. However, recent advances in bioelectronic medicine are changing this landscape. Multiple neuromodulation therapies that target circuits located in the brain, midbrain, or spinal cord have been able to improve motor and autonomic functions. The spectrum of implantable brain-computer interface technologies is also expanding at a fast pace, and all these neurotechnologies are being progressively embedded within rehabilitation programs in order to augment plasticity of spared circuits and residual projections with training. Here, we summarize the impending arrival of bioelectronic medicine in the field of SCI. We also discuss the new role of functional neurosurgeons in neurorestorative interventional medicine, a new discipline at the intersection of neurosurgery, neuro-engineering, and neurorehabilitation. |
format | Online Article Text |
id | pubmed-7098222 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-70982222020-03-30 Neurorestorative interventions involving bioelectronic implants after spinal cord injury Cho, Newton Squair, Jordan W. Bloch, Jocelyne Courtine, Grégoire Bioelectron Med Review In the absence of approved treatments to repair damage to the central nervous system, the role of neurosurgeons after spinal cord injury (SCI) often remains confined to spinal cord decompression and vertebral fracture stabilization. However, recent advances in bioelectronic medicine are changing this landscape. Multiple neuromodulation therapies that target circuits located in the brain, midbrain, or spinal cord have been able to improve motor and autonomic functions. The spectrum of implantable brain-computer interface technologies is also expanding at a fast pace, and all these neurotechnologies are being progressively embedded within rehabilitation programs in order to augment plasticity of spared circuits and residual projections with training. Here, we summarize the impending arrival of bioelectronic medicine in the field of SCI. We also discuss the new role of functional neurosurgeons in neurorestorative interventional medicine, a new discipline at the intersection of neurosurgery, neuro-engineering, and neurorehabilitation. BioMed Central 2019-07-11 /pmc/articles/PMC7098222/ /pubmed/32232100 http://dx.doi.org/10.1186/s42234-019-0027-x Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Cho, Newton Squair, Jordan W. Bloch, Jocelyne Courtine, Grégoire Neurorestorative interventions involving bioelectronic implants after spinal cord injury |
title | Neurorestorative interventions involving bioelectronic implants after spinal cord injury |
title_full | Neurorestorative interventions involving bioelectronic implants after spinal cord injury |
title_fullStr | Neurorestorative interventions involving bioelectronic implants after spinal cord injury |
title_full_unstemmed | Neurorestorative interventions involving bioelectronic implants after spinal cord injury |
title_short | Neurorestorative interventions involving bioelectronic implants after spinal cord injury |
title_sort | neurorestorative interventions involving bioelectronic implants after spinal cord injury |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098222/ https://www.ncbi.nlm.nih.gov/pubmed/32232100 http://dx.doi.org/10.1186/s42234-019-0027-x |
work_keys_str_mv | AT chonewton neurorestorativeinterventionsinvolvingbioelectronicimplantsafterspinalcordinjury AT squairjordanw neurorestorativeinterventionsinvolvingbioelectronicimplantsafterspinalcordinjury AT blochjocelyne neurorestorativeinterventionsinvolvingbioelectronicimplantsafterspinalcordinjury AT courtinegregoire neurorestorativeinterventionsinvolvingbioelectronicimplantsafterspinalcordinjury |