Amiodarone-Induced Acute Liver Injury

Amiodarone is a lipophilic structure with a half-life of 25–100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity. Intravenous amiodarone can lead to sweating, heating sensation, nausea, phlebitis at the injection site, and r...

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Autores principales: Essrani, Rajesh, Mehershahi, Shehriyar, Essrani, Rajesh Kumar, Ravi, Shri Jai Kirshan, Bhura, Sajeer, Sudhakaran, Anuraj, Hossain, Muhammad, Mehmood, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098330/
https://www.ncbi.nlm.nih.gov/pubmed/32231507
http://dx.doi.org/10.1159/000506184
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author Essrani, Rajesh
Mehershahi, Shehriyar
Essrani, Rajesh Kumar
Ravi, Shri Jai Kirshan
Bhura, Sajeer
Sudhakaran, Anuraj
Hossain, Muhammad
Mehmood, Asif
author_facet Essrani, Rajesh
Mehershahi, Shehriyar
Essrani, Rajesh Kumar
Ravi, Shri Jai Kirshan
Bhura, Sajeer
Sudhakaran, Anuraj
Hossain, Muhammad
Mehmood, Asif
author_sort Essrani, Rajesh
collection PubMed
description Amiodarone is a lipophilic structure with a half-life of 25–100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity. Intravenous amiodarone can lead to sweating, heating sensation, nausea, phlebitis at the injection site, and rarely acute hepatitis. This is a compelling case of a 60-year-old male who developed acute liver injury 24–36 h after starting amiodarone. All the possible causes of acute liver injury were ruled out, and his liver enzymes improved after discontinuing amiodarone.
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spelling pubmed-70983302020-03-30 Amiodarone-Induced Acute Liver Injury Essrani, Rajesh Mehershahi, Shehriyar Essrani, Rajesh Kumar Ravi, Shri Jai Kirshan Bhura, Sajeer Sudhakaran, Anuraj Hossain, Muhammad Mehmood, Asif Case Rep Gastroenterol Single Case Amiodarone is a lipophilic structure with a half-life of 25–100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity. Intravenous amiodarone can lead to sweating, heating sensation, nausea, phlebitis at the injection site, and rarely acute hepatitis. This is a compelling case of a 60-year-old male who developed acute liver injury 24–36 h after starting amiodarone. All the possible causes of acute liver injury were ruled out, and his liver enzymes improved after discontinuing amiodarone. S. Karger AG 2020-02-20 /pmc/articles/PMC7098330/ /pubmed/32231507 http://dx.doi.org/10.1159/000506184 Text en Copyright © 2020 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Essrani, Rajesh
Mehershahi, Shehriyar
Essrani, Rajesh Kumar
Ravi, Shri Jai Kirshan
Bhura, Sajeer
Sudhakaran, Anuraj
Hossain, Muhammad
Mehmood, Asif
Amiodarone-Induced Acute Liver Injury
title Amiodarone-Induced Acute Liver Injury
title_full Amiodarone-Induced Acute Liver Injury
title_fullStr Amiodarone-Induced Acute Liver Injury
title_full_unstemmed Amiodarone-Induced Acute Liver Injury
title_short Amiodarone-Induced Acute Liver Injury
title_sort amiodarone-induced acute liver injury
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098330/
https://www.ncbi.nlm.nih.gov/pubmed/32231507
http://dx.doi.org/10.1159/000506184
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