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Preregistration of exploratory research: Learning from the golden age of discovery
Preregistration of study protocols and, in particular, Registered Reports are novel publishing formats that are currently gaining substantial traction. Besides rating the research question and soundness of methodology over outstanding significance of the results, they can help with antagonizing inad...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098547/ https://www.ncbi.nlm.nih.gov/pubmed/32214315 http://dx.doi.org/10.1371/journal.pbio.3000690 |
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author | Dirnagl, Ulrich |
author_facet | Dirnagl, Ulrich |
author_sort | Dirnagl, Ulrich |
collection | PubMed |
description | Preregistration of study protocols and, in particular, Registered Reports are novel publishing formats that are currently gaining substantial traction. Besides rating the research question and soundness of methodology over outstanding significance of the results, they can help with antagonizing inadequate statistical power, selective reporting of results, undisclosed analytic flexibility, as well as publication bias. Preregistration works well when a clear hypothesis, primary outcome, and mode of analysis can be formulated. But is it also applicable and useful in discovery research, which develops theories and hypotheses, measurement techniques, and generates evidence that justifies further research? I will argue that only slight modifications are needed to harness the potential of preregistration and make exploratory research more trustworthy and useful. |
format | Online Article Text |
id | pubmed-7098547 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-70985472020-04-03 Preregistration of exploratory research: Learning from the golden age of discovery Dirnagl, Ulrich PLoS Biol Perspective Preregistration of study protocols and, in particular, Registered Reports are novel publishing formats that are currently gaining substantial traction. Besides rating the research question and soundness of methodology over outstanding significance of the results, they can help with antagonizing inadequate statistical power, selective reporting of results, undisclosed analytic flexibility, as well as publication bias. Preregistration works well when a clear hypothesis, primary outcome, and mode of analysis can be formulated. But is it also applicable and useful in discovery research, which develops theories and hypotheses, measurement techniques, and generates evidence that justifies further research? I will argue that only slight modifications are needed to harness the potential of preregistration and make exploratory research more trustworthy and useful. Public Library of Science 2020-03-26 /pmc/articles/PMC7098547/ /pubmed/32214315 http://dx.doi.org/10.1371/journal.pbio.3000690 Text en © 2020 Ulrich Dirnagl http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Perspective Dirnagl, Ulrich Preregistration of exploratory research: Learning from the golden age of discovery |
title | Preregistration of exploratory research: Learning from the golden age of discovery |
title_full | Preregistration of exploratory research: Learning from the golden age of discovery |
title_fullStr | Preregistration of exploratory research: Learning from the golden age of discovery |
title_full_unstemmed | Preregistration of exploratory research: Learning from the golden age of discovery |
title_short | Preregistration of exploratory research: Learning from the golden age of discovery |
title_sort | preregistration of exploratory research: learning from the golden age of discovery |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098547/ https://www.ncbi.nlm.nih.gov/pubmed/32214315 http://dx.doi.org/10.1371/journal.pbio.3000690 |
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