EpCAM-independent isolation of circulating tumor cells with epithelial-to-mesenchymal transition and cancer stem cell phenotypes using ApoStream(®) in patients with breast cancer treated with primary systemic therapy

BACKGROUND: Tumor cells with a mesenchymal phenotype and/or cancer stem-like cells (CSCs) are known to contribute to metastasis and drug resistance. Circulating tumor cells (CTCs) undergoing epithelial-mesenchymal transition (EMT) and CTCs reflecting a dedifferentiated CSC phenotype may not be detec...

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Detalles Bibliográficos
Autores principales: Le Du, Fanny, Fujii, Takeo, Kida, Kumiko, Davis, Darren W., Park, Minjeong, Liu, Diane D., Wu, Weiguo, Chavez-MacGregor, Mariana, Barcenas, Carlos H., Valero, Vicente, Tripathy, Debu, Reuben, James M., Ueno, Naoto T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098555/
https://www.ncbi.nlm.nih.gov/pubmed/32214335
http://dx.doi.org/10.1371/journal.pone.0229903

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