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Inhibiting of self-renewal, migration and invasion of ovarian cancer stem cells by blocking TGF-β pathway

OBJECTIVE: To investigate the effect and mechanism of SB525334 on self-renewal, migration and invasion of ovarian cancer stem cells. METHODS: ALDHhigh-expressing cancer stem cells (CSCs) were isolated from human ovarian cancer cell line SKOV-3 by flow cytometry and treated with 2μg/mL SB525334 for 6...

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Detalles Bibliográficos
Autores principales:	Wen, Haiyan, Qian, Min, He, Jing, Li, Meihui, Yu, Qing, Leng, Zhengwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098562/ https://www.ncbi.nlm.nih.gov/pubmed/32214328 http://dx.doi.org/10.1371/journal.pone.0230230

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