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Stochastic simulation and statistical inference platform for visualization and estimation of transcriptional kinetics
Recent advances in single-molecule fluorescent imaging have enabled quantitative measurements of transcription at a single gene copy, yet an accurate understanding of transcriptional kinetics is still lacking due to the difficulty of solving detailed biophysical models. Here we introduce a stochasti...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098607/ https://www.ncbi.nlm.nih.gov/pubmed/32214380 http://dx.doi.org/10.1371/journal.pone.0230736 |