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Creation of different bioluminescence resonance energy transfer based biosensors with high affinity to VEGF

In age-related macular degeneration (AMD) or diabetic retinopathy (DR), hypoxia and inflammatory processes lead to an upregulation of the vascular endothelial growth factor (VEGF) expression and thereby to pathological neovascularisation with incorrectly formed vessels prone to damage, thus increasi...

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Detalles Bibliográficos
Autores principales: Stumpf, Constanze, Wimmer, Tobias, Lorenz, Birgit, Stieger, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098639/
https://www.ncbi.nlm.nih.gov/pubmed/32214330
http://dx.doi.org/10.1371/journal.pone.0230344